Titans vs Bills Monday Night Football Picks and Predictions: Tannehill Gets Roughed Up

Welcome to our free NFL betting picks and predictions for the Tennessee Titans vs. Buffalo Bills, the first of two Monday Night Football games tonight.

The Bills proved they deserve to be atop the Super Bowl odds board by making a huge statement in the 2022 season opener last Thursday. 

Buffalo blasted the reigning champion L.A. Rams on the road in Week 1 and now sets its sights on last year’s top seed in the AFC — the Titans — in Week 2. 

The Bills have had a mini bye to prep for their home opener, which is one of the reasons why this line is rising toward the host team. Tennessee’s Week 1 effort against the N.Y. Giants isn’t helping the case for the visitor, as the Titans blew a 13-0 second-half advantage and lost 21-20 as 5.5-point home chalk.

In addition to analyzing the Over/Under total, our best bet is a prop focusing on a quarterback who may struggle to get things going in the air tonight.

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